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Two spotted Spider Mites build resistance to most insecticides, however, there is one insecticide that they do not build a resistance to DEAD RED, THIS IS THE STUFF! Spider Mites do not build a resistance to this product.  It stops them from feeding instantly, death follows within hours.  It has a 7 day residual on plants.  It's a naturally derived substance produced by soil micro-organismsstreptomyces avermitilis and also deals death to leaf miners.

When applying pesticides to your plants be careful of phytotoxicity, all pesticides are phytotoxic, some a lot more than others. Phytotoxicity is the damage caused when pesticides are applies to your plants. The chemicals along with intense light, H.I.D lights or the sun, can cause your plants and leaves to burn or even kill your plants. To avoid this turn on some regular light bulbs in your grow room to hold your plants in there proper light cycle. You should allow 4 - 8 hours to pass before turning your H.I.D lights back on. When applying pesticides you should wear a respirator and protective clothing.

When applying insecticides, thoroughly drench your plants and LIGHTS OFF. Remember spider mites live on the underside of the plant leaves.